PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL EVALUATION OF PSEUDARTHRIA VISCIDA LINN
Keywords:
Anti-inflammatory activity, Carrageenan Induced paw edema model, Indomethacin, Pseudarthria viscida.Abstract
Pseudarthria viscida had been widely used for its reported biological activities in indigenous system of medicine. The present investigation was
carried out to find the effect of ethanol extract of Pseudarthria viscida (EEPV) for its anti-inflammatory activity in rat. In this study, the antiinflammatory activity of Pseudarthria viscida was evaluated by using a carrageenan-induced rat paw edema model and compared with that of
standard drug Indomethacin. Oral administration of the extract at the doses 200 and 400 mg/kg b.w. exhibited dose dependent and significant antiinflammatory activity in carrageenan-induced hind paw edema of inflammation. Both the dose of Pseudarthria viscida promoted the antiinflammatory activity significantly when compared to the standard drug. Hence, present investigation established some pharmacological evidences
to support the folklore claim that Pseudarthria viscida is used as anti-inflammatory agent.
